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If you must take a drug that has the potential to interact with your existing medicationsyour doctor can do the following:

It may also be necessary to avoid drugs that do not affect indinavir drug levelsbut cause similar side effects.

Get emergency medical help if you have any of these signs of an allergic reactionhivesdifficulty breathingswelling of your facelipstongueor throat.

Midazolam is extensively metabolized by CYP3A4Co-administration with CRIXIVAN with or without ritonavir may cause a large increase in the concentration of this benzodiazepineNo drug interaction study has been performed for the co-administration of CRIXIVAN with benzodiazepinesBased on data from other CYP3A4 inhibitorsplasma concentrations of midazolam are expected to be significantly higher when midazolam is given orallyTherefore CRIXIVAN should not be co-administered with orally administered midazolamsee CONTRAINDICATIONSwhereas caution should be used with coadministration of CRIXIVAN and parenteral midazolamData from concomitant use of parenteral midazolam with other protease inhibitors suggest a possible 3-4 fold increase in midazolam plasma levelsIf CRIXIVAN with or without ritonavir is co-administered with Atrovent purchase parenteral midazolamit should be done in a setting which ensures close clinical monitoring and appropriate medical management in case of respiratory depression and/or prolonged sedationDosage reduction for midazolam should be consideredespecially if more than a single dose of midazolam is administered.

When HIV becomes resistant to one drug in a classit sometimes becomes resistant to other drugs in that classThis is called cross-resistanceFeel free to talk with your doctor about your current and future treatment optionsTo help you decide what these future therapies might beat some point your doctor can have a small sample of your blood analysed using resistance testingShould HIV in your body become resistant to indinavir your doctorwith the help of resistance testingcan help put together a new treatment regimen for you.

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deflazacort is a cyp3a4 substrate; indinavir is a strong inhibitor of cyp3a4. " download>Download